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Hemoglobin (haemoglobin, [a] Hb or Hgb) is a protein containing iron that facilitates the transportation of oxygen in red blood cells. Almost all vertebrates contain hemoglobin, [3] with the sole exception of the fish family Channichthyidae. [4]
Iron deficiency first affects the storage of iron in the body, and depletion of these stores is thought to be relatively asymptomatic, although some vague and non-specific symptoms have been associated with it. Since iron is primarily required for hemoglobin, iron deficiency anemia is the primary clinical manifestation of iron deficiency. Iron ...
Iron deficiency anemia is the most common anemia; it occurs when the dietary intake or absorption of iron is insufficient, and hemoglobin, which contains iron, cannot be formed. Pernicious anemia is an autoimmune disease wherein the body lacks intrinsic factor , required to absorb vitamin B 12 from food.
The most common type is iron-deficiency anemia, in which a lack of iron leads to a reduction in the number of red blood cells or hemoglobin. This can impair oxygen transport throughout the body.
Iron deficiency first affects the storage of iron in the body, and depletion of these stores is thought to be relatively asymptomatic, although some vague and non-specific symptoms have been associated with it. Since iron is primarily required for hemoglobin, iron deficiency anemia is the primary clinical manifestation of iron deficiency. Iron ...
The structure of adult human hemoglobin. α and β subunits are shown in red and blue, and the iron-containing heme groups in green. From PDB: 1GZX Proteopedia Hemoglobin. Hemoglobin A (HbA), also known as adult hemoglobin, hemoglobin A1 or α 2 β 2, is the most common human hemoglobin tetramer, accounting for over 97% of the total red blood ...
Hemoglobin has an oxygen binding capacity between 1.36 and 1.40 ml O 2 per gram hemoglobin, [23] which increases the total blood oxygen capacity seventyfold, [24] compared to if oxygen solely were carried by its solubility of 0.03 ml O 2 per liter blood per mm Hg partial pressure of oxygen (about 100 mm Hg in arteries). [24]
A meta-analysis showed that pulse intake was linked to improved glucose responses, and long-term trials reported meaningful improvements in hemoglobin A1C, fasting glucose, fasting insulin and ...
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