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BLAT connects each homologous area between two sequences into a single larger alignment, in contrast to BLAST which returns each homologous area as a separate local alignment. The result of BLAST is a list of exons with each alignment extending just past the end of the exon.
While BLAST does a linear search, BLAT relies on k-mer indexing the database, and can thus often find seeds faster. [22] Another software alternative similar to BLAT is PatternHunter . Advances in sequencing technology in the late 2000s has made searching for very similar nucleotide matches an important problem.
It makes use of the BLAST [5] algorithm to identify similar sequences to then transfers existing functional annotation from yet characterised sequences to the novel one. The functional information is represented via the Gene Ontology (GO), a controlled vocabulary of functional attributes.
Distributed with the latest version of BLAST, this wrapper facilitates parallelization of the algorithm on modern hybrid architectures with many nodes and many cores within each node. [2] Protein: Burdyshaw CE, Sawyer S, Horton MD, Brook RG, Rekapalli B: 2017 CS-BLAST: Sequence-context specific BLAST, more sensitive than BLAST, FASTA, and SSEARCH.
BLAST (biotechnology), Basic Local Alignment Search Tool, an algorithm used in bioinformatics; Blast cell or precursor cell, in cytology, a type of partially differentiated, usually unipotent cell; Blast disease, a disease of cereal crops; Blast injury, a complex type of physical trauma resulting from direct or indirect exposure to an explosion
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Bell Laboratories Layer Space-Time (BLAST) is a transceiver architecture for offering spatial multiplexing over multiple-antenna wireless communication systems. Such systems have multiple antennas at both the transmitter and the receiver in an effort to exploit the many different paths between the two in a highly- scattering wireless environment.
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