enow.com Web Search

Search results

1. Results from the WOW.Com Content Network

2. Immune system contribution to regeneration - Wikipedia

   en.wikipedia.org/wiki/Immune_system_contribution...

   Both phenotypes of macrophages (M1 and M2) are one of the most important regenerative components of the immune system as their dysfunction inhibits tissue repair and blastema formation. M1 macrophages are known as pro-inflammatory, (secreting cytokines IL-1, IL-6, TNF- α, and IFN-γ) playing a crucial role in pathogen phagocytosis and cell ...

3. Tissue remodeling - Wikipedia

   en.wikipedia.org/wiki/Tissue_remodeling

   Macrophages repair wounds and remodel tissue by producing extracellular matrix and proteases to modify that specific matrix. [1] A myocardial infarction induces tissue remodeling of the heart in a three-phase process: inflammation, proliferation, and maturation. Inflammation is characterized by massive necrosis in the infarcted area ...

4. Macrophage - Wikipedia

   en.wikipedia.org/wiki/Macrophage

   In contrast, the M2 "repair" designation (also referred to as alternatively activated macrophages) broadly refers to macrophages that function in constructive processes like wound healing and tissue repair, and those that turn off damaging immune system activation by producing anti-inflammatory cytokines like IL-10.

5. New biodegradable gel could ‘repair damage caused by heart ...

   www.aol.com/biodegradable-gel-could-repair...

   A new biodegradable gel has been developed to repair the damage caused by a heart attack. Experts at the University of Manchester, backed by the British Heart Foundation (BHF), created the ...

6. Macrophage polarization - Wikipedia

   en.wikipedia.org/wiki/Macrophage_polarization

   Macrophage polarization is a process by which macrophages adopt different functional programs in response to the signals from their microenvironment. This ability is connected to their multiple roles in the organism: they are powerful effector cells of the innate immune system, but also important in removal of cellular debris, embryonic development and tissue repair.

7. Healing - Wikipedia

   en.wikipedia.org/wiki/Healing

   Failure to remove all of the damaged cells and pathogens may retrigger inflammation. The two subsets of macrophage M1 & M2 plays a crucial role in this phase, M1 macrophage being a pro inflammatory while as M2 is a regenerative and the plasticity between the two subsets determine the tissue inflammation or repair. [citation needed]

8. Apoptosis inhibitor of macrophage - Wikipedia

   en.wikipedia.org/wiki/Apoptosis_inhibitor_of...

   AIM is highly expressed in foam macrophages within atherosclerotic plaques, promoting macrophage survival and inflammatory responses. AIM deficiency in mice shows improved outcomes after myocardial infarction, including increased survival, reduced heart rupture, and altered macrophage profiles.

9. Abbott's heart valve repair device gets FDA advisers' backing

   www.aol.com/news/abbotts-heart-valve-repair...

   Advisers to the U.S. Food and Drug Administration on Tuesday backed an approval for Abbott Laboratories' heart valve repair device that is designed for patients who are at risk of complications or ...