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Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease sensation in a specific small area. [5] In nerve blocks, it is injected around a nerve that supplies the area, or into the spinal canal's epidural space. [5] It is available mixed with a small amount of epinephrine to increase the duration of its ...
Cinchocaine (INN/BAN) or dibucaine is an amide local anesthetic.Among the most potent and toxic of the long-acting local anesthetics, current use of cinchocaine is generally restricted to spinal and topical anesthesia.
Topical hydrocortisone is formulated as liquid, solution, lotion, cream, gel, ointment, foam, and spray. [33] The strength of topical hydrocortisone products ranges from 0.1% to 2.5%, which means there could be 1 mg to 25 mg hydrocortisone in 1g of the products. [ 12 ]
Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCl) is a topical anesthetic discovered at Abbott Laboratories in 1953 [1] and used as an antipruritic.During research and development, pramocaine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent. [1]
name UK Trade name Concentration (%) Maximum dose (mg/kg) Articaine with adrenaline Bartinest Septanest 4 7 Bupivacaine Marcain 0.25 2.5 Lidocaine 1 3 2 Lidocaine with adrenaline Utilycaine Lignospan Special Xylocaine 1 7 2 Mepivacaine Scandonest 2 1.36 (3 mg per pound), less than 400 mg in adults 3 Prilocaine with Felypressin Citanest 0.5 7 1
Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [ 3 ] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
Proxymetacaine is available as its hydrochloride salt in ophthalmic solutions at a concentration of 0.5%. Although it is no longer on patent, it is still marketed under the trade names Alcaine, Ak-Taine, and others. Proparacaine 0.5% is marketed as Poencaina by Poen Laboratories. [5]
Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery. [1] [2] It may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for. [2]
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