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  2. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    Loop diuretics usually have a ceiling effect whereby doses greater than a certain maximum amount will not increase the clinical effect of the drug. Also, there is a threshold minimum concentration of loop diuretics that needs to be achieved at the thick ascending limb to enable the onset of abrupt diuresis. [10]

  3. Hypermagnesemia - Wikipedia

    en.wikipedia.org/wiki/Hypermagnesemia

    The use of diuretics must be associated with infusions of saline solutions to avoid further electrolyte disturbances (e.g., hypokalemia) and metabolic alkalosis. The clinician must perform serial measurements of calcium and magnesium. In association with electrolytic correction, it is often necessary to support cardiorespiratory activity.

  4. Furosemide - Wikipedia

    en.wikipedia.org/wiki/Furosemide

    As with many diuretics, it can cause dehydration and electrolyte imbalance, including loss of potassium, calcium, sodium, and magnesium. Excessive use of furosemide will most likely lead to a metabolic alkalosis due to hypochloremia and hypokalemia. The drug should, therefore, not be used in horses that are dehydrated or experiencing kidney ...

  5. Gitelman syndrome - Wikipedia

    en.wikipedia.org/wiki/Gitelman_syndrome

    The effect is an electrolyte imbalance similar to that seen with thiazide diuretic therapy (which causes pharmacological inhibition of NCC activity). [ 4 ] Gitelman syndrome was formerly considered a subset of Bartter syndrome until the distinct genetic and molecular bases of these disorders were identified.

  6. Electrolyte imbalance - Wikipedia

    en.wikipedia.org/wiki/Electrolyte_imbalance

    These electrolytes must be replaced to keep the electrolyte concentrations of the body fluids constant. Hyponatremia, or low sodium, is the most commonly seen type of electrolyte imbalance. [12] [13] Treatment of electrolyte imbalance depends on the specific electrolyte involved and whether the levels are too high or too low. [3]

  7. Metabolic alkalosis - Wikipedia

    en.wikipedia.org/wiki/Metabolic_alkalosis

    Diuretic therapy – loop diuretics and thiazides can both initially cause increase in chloride, but once stores are depleted, urine excretion will be below < 25 mEq/L. The loss of fluid from sodium excretion causes a contraction alkalosis. Diuretic abuse among athletes [4] and people with eating disorders [5] may present with metabolic alkalosis.

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  9. Bendroflumethiazide - Wikipedia

    en.wikipedia.org/wiki/Bendroflumethiazide

    Bendroflumethiazide is a thiazide diuretic which works by inhibiting sodium reabsorption at the beginning of the distal convoluted tubule (DCT). Water is lost as a result of more sodium reaching the collecting ducts. Bendroflumethiazide has a role in the treatment of mild heart failure although loop diuretics are better

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