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An estrogen (E) is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy, and as part of feminizing hormone therapy for transgender women. [1] They can also be used in the treatment of hormone-sensitive cancers like breast cancer and prostate cancer and for various other indications.
Estradiol is an estrogen, or an agonist of the estrogen receptors (ERs), the ERα Tooltip estrogen receptor alpha and ERβ Tooltip estrogen receptor beta. [11] It is also an agonist of membrane estrogen receptors (mERs), including the GPER Tooltip G protein-coupled estrogen receptor , G q -mER Tooltip Gq-coupled membrane estrogen receptor , ER ...
It is an estrogen, or an agonist of the estrogen receptors, the biological target of estrogens like estradiol. [5] [3] [4] EEs are a prodrug mainly of estradiol and to a lesser extent of equilin. [5] EEs were introduced for medical use by 1970. [9] They are available in only a few countries, such as Chile and the United States. [3]
Atypical (dual estrogen and nitrogen mustard alkylating antineoplastic): Estramustine phosphate sodium (Emcyt) – 140 mg; Oral estradiol valerate (except in combination with dienogest as an oral contraceptive) is not available in the U.S. and is used primarily in Europe. [2]
Estradiol is an estrogen, or an agonist of the nuclear estrogen receptors (ERs), the estrogen receptor alpha (ERα) and the estrogen receptor beta (ERβ). [1] [2] [6] In one study, the EC 50 Tooltip half-maximal effective concentration value of estradiol for the human ERα was 50 pM (0.05 nM) and for the human ERβ was 200 pM (0.2 nM).
Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body. They act by blocking the estrogen receptor (ER) and/or inhibiting or suppressing estrogen production .
Estrogen (medication) Estrogen and neurodegenerative diseases; Estrogen conjugate; Estrogen ester; Estrogen insensitivity syndrome; Estrogen patch; Estrogen provocation test; Template:Estrogen receptor modulators; Estrogen-dependent condition; Estrogenic substances; Estromustine; Estrone; Estrone (medication) Estrone acetate; Estrone cyanate ...
Estradiol/progesterone (E2/P4), sold under the brand name Bijuva among others, is a combined estrogen and progestogen medication which is used in the treatment of menopausal symptoms in postmenopausal women. [3] It contains estradiol, an estrogen, and progesterone, a progestogen, and is available in both oral and intramuscular formulations. [3]