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Chromium toxicity refers to any poisonous toxic effect in an organism or cell that results from exposure to specific forms of chromium—especially hexavalent chromium. [1] Hexavalent chromium and its compounds are toxic when inhaled or ingested. Trivalent chromium is a trace mineral that is essential to human
Many metals, particularly heavy metals are toxic, but some are essential, and some, such as bismuth, have a low toxicity. Metals in an oxidation state abnormal to the body may also become toxic: chromium(III) is an essential trace element, but chromium(VI) is a carcinogen. Only soluble metal-containing compounds are toxic.
This study looks at chronic oral exposure of hexavalent chromium in rats, and its association with cancer. The other study mentioned is a human health assessment of chromium, titled Toxicological Review of Hexavalent Chromium. The final human health assessment is currently in the stage of draft development. [47] This stage is the first of seven.
Hexavalent chromium is a well-known pollutant because it was the central chemical in the class-action lawsuit depicted in the film “Erin Brockovich” over chromium pollution in water in Hinkley ...
Broadly, long-term exposure to toxic heavy metals can have carcinogenic, central and peripheral nervous system, and circulatory effects. For humans, typical presentations associated with exposure to any of the "classical" [37] toxic heavy metals, or chromium (another toxic heavy metal) or arsenic (a metalloid), are shown in the table. [38]
A 2007 toxicity report for the National Toxicology Program provided evidence that high doses of chromium 6 caused cancers of the gastrointestinal tract in rats and mice at levels higher than 5 mg/L of water, (5 ppm, or 5,000 ppb). [41] [42] Average hexavalent chromium levels in Hinkley were recorded at 1.19 ppb, with an estimated peak of 20 ppb.
Feb. 12—The public will have an additional month to weigh in on a federal report assessing the possible impacts of the latest proposed measures for cleaning up a toxic chromium plume beneath Los ...
Ingestion of, or exposure to, excessive quantities can be toxic. However, insufficient plasma or tissue levels of certain trace metals can cause pathology, as is the case with iron. Trace metals within the human body include iron, lithium, zinc, copper, chromium, nickel, cobalt, vanadium, molybdenum, manganese and others. [1] [2] [3]