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Ricin (/ ˈ r aɪ s ɪ n / RY-sin) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, Ricinus communis.The median lethal dose (LD 50) of ricin for mice is around 22 micrograms per kilogram of body weight via intraperitoneal injection.
Currently, no effective antidote exists for the treatment of batrachotoxin poisoning. [11] Veratridine, aconitine and grayanotoxin—like batrachotoxin—are lipid-soluble poisons which similarly alter the ion selectivity of the sodium channels, suggesting a common site of action. Due to these similarities, treatment for batrachotoxin poisoning ...
Another antidote developed by the U.S. military has been shown to be safe and effective in lab mice injected with antibody-rich blood mixed with ricin, and has had some human testing. Symptomatic and supportive treatments are available for ricin poisoning, but there is no antidote for ricin available for humans.
Most victims die between 36 and 72 hours after exposure and there is no known antidote. "Ricin is not infectious between people and the risk to the wider public based on the information available ...
Axel Rudakubana, 18, will appear at Westminster Magistrates’ Court by video link on Wednesday charged with production of a biological toxin called ricin
A letter addressed to the president that was intercepted before it reached the White House tested positive for the deadly poison ricin, officials said.
Ricin quickly and irreversibly inhibits ribosomes, the molecular machines responsible for producing proteins in all cells. [174] The LD 50 in adults is only about 22 μg/kg when injected or inhaled; ingested ricin is much less toxic due to the digestive activity of peptidases , although a dose of 20 to 30 mg/kg, or about 4 to 8 seeds, can still ...
An antidote is a substance that can counteract a form of poisoning. [1] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton) , "(medicine) given as a remedy".