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The amygdala, cerebellum, and many other brain regions have been implicated in autism. [15]Unlike some brain disorders which have clear molecular hallmarks that can be observed in every affected individual, such as Alzheimer's disease or Parkinson's disease, autism does not have a unifying mechanism at the molecular, cellular, or systems level.
Many causes of autism, including environmental and genetic factors, have been recognized or proposed, but understanding of the theory of causation of autism is incomplete. [1] Attempts have been made to incorporate the known genetic and environmental causes into a comprehensive causative framework. [ 2 ]
Animal Science Image Gallery - a work of the United States Federal Government—containing images, animations, and video for classroom and outreach learning Bioinformatic Harvester - was a bioinformatic meta search engine at KIT Karlsruhe Institute of Technology —working for human, mouse, rat, zebrafish, drosophila and arabidopsis thaliana ...
Approximately 20% of autistic children have megalencephaly, making it the most common physical characteristic of autism. [6] People who present both megalencephaly and autistic characteristics usually also show signs of hyperactivity as a major symptom. However, there is no definitive evidence that autism is the primary cause/result of ...
In the animal models, the significant effects of VPA in causing ASD-like symptoms was demonstrated mainly in rats exposed to VPA on gestation day 12.5, not in other gestation days like day 9, 14.5, etc. [47] [48] The ASD-like symptoms of mice included decreased distressed pup calls, decreased social exploration, decreased social behaviors ...
The review found that CBT was moderately to highly effective at reducing anxiety in school children with autism spectrum disorder, but that effects varied depending on whether they were reported by clinicians, parents or self-reported. Treatments involving parents and one-on-one compared to group treatments were more effective. [12]
The exact cause of autism, including what was formerly known as Asperger syndrome, is not well understood. [5] While it has high heritability, the underlying genetics have not been determined conclusively. [19] [20] Environmental factors are also believed to play a role. [5] Brain imaging has not identified a common underlying condition. [19]
Autism has multiple causes. This article focuses on heritable causes. The heritability of autism is the proportion of differences in expression of autism that can be explained by genetic variation; if the heritability of a condition is high, then the condition is considered to be primarily genetic. Autism has a strong genetic basis.