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Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life. Two segments of DNA can have shared ancestry because of three phenomena: either a speciation event (orthologs), or a duplication event (paralogs), or else a horizontal (or lateral) gene ...
Orthology or paralogy inference requires an assessment of sequence homology, usually via sequence alignment. Phylogenetic analyses and sequence alignment are often considered jointly, as phylogenetic analyses using DNA or RNA require sequence alignment and alignments themselves often represent some hypothesis of homology.
Homology in psychology, as in biology, refers to a relationship between characteristics that reflects the characteristics' origins in either evolution or development. Homologous behaviors can theoretically be of at least two different varieties. [ 1 ]
In the genomic branch of bioinformatics, homology is used to predict the function of a gene: if the sequence of gene A, whose function is known, is homologous to the sequence of gene B, whose function is unknown, one could infer that B may share A's function. In structural bioinformatics, homology is used to determine which parts of a protein ...
A profile HMM modelling a multiple sequence alignment. HMMER is a free and commonly used software package for sequence analysis written by Sean Eddy. [2] Its general usage is to identify homologous protein or nucleotide sequences, and to perform sequence alignments.
Homology (psychology), behavioral characteristics that have common origins in either evolution or development Homologous behaviors , behaviors typical of species that share a common ancestor that was characterized by that behavior OR behaviors in an individual that share common origins in development
Homology model of the DHRS7B protein created with Swiss-model and rendered with PyMOL. Homology modeling, also known as comparative modeling of protein, refers to constructing an atomic-resolution model of the "target" protein from its amino acid sequence and an experimental three-dimensional structure of a related homologous protein (the "template").
[158] [159] The Sequence Analysis Association (SAA) was founded at the International Symposium on Sequence Analysis and Related Methods, in October 2018 at Monte Verità, TI, Switzerland. The SAA is an international organization whose goal is to organize events such as symposia and training courses and related events, and to facilitate scholars ...