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26417 Ensembl ENSG00000102882 ENSMUSG00000063065 UniProt P27361 Q63844 RefSeq (mRNA) NM_001040056 NM_001109891 NM_002746 NM_011952 RefSeq (protein) NP_001035145 NP_001103361 NP_002737 NP_036082 Location (UCSC) Chr 16: 30.11 – 30.12 Mb Chr 7: 126.36 – 126.36 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Mitogen-activated protein kinase 3, also known as p44MAPK and ERK1, is an ...
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines.
Mitogen-activated protein kinase 3 (MAPK3) is also known as extracellular signal-regulated kinase 1 (ERK1). Transgenic gene knockout mice lacking MAPK3 are viable and it is thought that MAPK1 can fulfill some MAPK3 functions in most cells. [11] The main exception is in T cells. Mice lacking MAPK3 have reduced T cell development past the CD4 ...
Perhaps the best characterized MAP3K are the members of the oncogenic RAF family (RAF1, BRAF, ARAF), which are effectors of mitogenic ras signaling and which activate the ERK1/2 (MAPK3/MAPK1) pathway, through activation of MEK1(MAP2K1) and MEK2(MAP2K2). The JNKs are regulated by the MEKK 1/4, MLK 2/3, and ASK 1 MAPKKKs.
26406 Ensembl ENSG00000198909 ENSMUSG00000020700 UniProt Q99759 Q61084 RefSeq (mRNA) NM_002401 NM_203351 NM_001330431 NM_001363768 NM_011947 RefSeq (protein) NP_001317360 NP_002392 NP_976226 NP_001350697 NP_036077 Location (UCSC) Chr 17: 63.62 – 63.7 Mb Chr 11: 105.98 – 106.05 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Mitogen-activated protein kinase kinase kinase 3 is an ...
102626 Ensembl ENSG00000114738 ENSMUSG00000032577 UniProt Q16644 Q3UMW7 RefSeq (mRNA) NM_001243925 NM_001243926 NM_004635 NM_178907 NM_001316691 RefSeq (protein) NP_001230854 NP_001230855 NP_004626 NP_001303620 NP_849238 Location (UCSC) Chr 3: 50.61 – 50.65 Mb Chr 9: 107.13 – 107.17 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse MAP kinase-activated protein kinase 3 is an enzyme ...
Studies show that keeping your head at the appropriate height—about 2 inches (or 5 centimeters) off the bed—helps air flow into the lungs and stabilizes your respiratory function. However ...
Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK). ...