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Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF). It is useful in several applications, such as for spinal anesthesia, chemotherapy, or pain management. This route is also used to introduce drugs that fight ...
High flow rates are attainable with an IO infusion, up to 125 milliliters per minute. This high rate of flow is achieved using a pressure bag to administer the infusion directly into the bone. Large volume IO infusions are known to be painful. 1% lidocaine is used to ease the pain associated with large volume IO infusions in conscious people. [3]
Local anesthetic injections are given in specific areas of the mouth, rather than the whole body. Although several different medications are available, the most commonly used local anesthetic to prevent pain in the area around a tooth is lidocaine (also called xylocaine or lignocaine). Lidocaine's half-life in the body is about 1.5–2 hours. [2]
[7] Most commonly, hyperosmolar dextrose (a sugar) is the solution used; [23] glycerine, [20] lidocaine (a commonly used local anesthetic), [24] phenol, [20] and sodium morrhuate (a derivative of cod liver oil extract) are other commonly used agents. [7] [9] The injection is administered at joints, ligaments, or tendons where they connect to bone.
Lidocaine is an antiarrhythmic medication of the class Ib type. [7] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart. [10] [7] When injected near nerves, the nerves cannot conduct signals to or from the brain. [8] Lidocaine was discovered in 1946 and went on sale in 1948. [11]
Lidocaine “might be useful for reducing patient pain” when injected as a local anesthetic or applied topically as a numbing gel, cream or spray, the CDC said in the update, the first since 2016.
Single-injection techniques provide unreliable blockade in the areas supplied by the musculocutaneous and radial nerves. Current evidence suggests that a triple-stimulation technique — with injections on the musculocutaneous, median and radial nerves — is the best technique for the axillary block.
A nerve block is the use of local anesthetic (e.g lidocaine) to inhibit the sensation of pain caused by one or multiple nerves. [2] A nerve block can help doctors confirm what nerve is causing the pain to support a diagnosis. A nerve block can also be used to prevent pain before a procedure, or relieve chronic pain. [2]