Search results
Results from the WOW.Com Content Network
Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative. It is a first-generation H 1 -antihistamine and it works by blocking certain effects of histamine , which produces its antihistamine and sedative effects.
Benadryl can also be found in a topical form including gels and creams. Benadryl Itch Stopping Cream is a topical cream used to provide temporary itch relief for allergies, hives or even some insect bites. It can be found in the United States and Canada. This topical medication contains 2% of diphenhydramine hydrochloride and 1% of zinc acetate.
Main page; Contents; Current events; Random article; About Wikipedia; Contact us
Diphenhydramine (Benadryl) was synthesized in 1943, tripelennamine (Pyribenzamine) was patented in 1946, and promethazine (Phenergan) was synthesized in 1947 and launched in 1949. [22] [23] [24] By 1950, at least 20 antihistamines had been marketed. [25]
ATC code R06 Antihistamines for systemic use is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Dimenhydrinate is a theoclate salt composed of diphenhydramine and 8-chlorotheophylline (a theophylline relative) in a 1:1 ratio. [ 2 ] Dimenhydrinate was introduced to the market by G.D. Searle in 1949.
In 1943, one of his students, Fred Huber, synthesized diphenhydramine. Rieveschl worked with Parke-Davis to test the compound, and the company licensed the patent from him. In 1947 Parke-Davis hired him as their director of research. While he was there, he led the development of a similar drug, orphenadrine. [5]
Diphenhydramine (often referred to by the trade name Benadryl) is an anticholinergic antihistamine medicine commonly used to treat allergic reactions and symptoms of a common cold, such as coughing. Its central antihistaminergic properties also cause it to act as a sedative, and for this reason it is also used to treat insomnia. [24]