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Permanent damage to these beta cells results in Type 1, or insulin-dependent diabetes, for which exogenous insulin replacement therapy is the only answer. Diabetes mellitus is a disease in which the beta cells of the endocrine pancreas either stop producing insulin or can no longer produce it in enough quantity for the body's needs. The disease ...
Most cataracts in dogs are caused by a genetic predisposition, but diabetes mellitus is also a common cause. [65] The only effective treatment is surgical removal. [66] Lens luxation is a displacement of the lens from its normal position. Terrier breeds are predisposed. [63] Nuclear sclerosis is a consistent finding in dogs greater than seven ...
Discoid lupus erythematosus (DLE) is an uncommon autoimmune disease of the basal cell layer of the skin. It occurs in humans [1] and cats, more frequently occurring in dogs. It was first described in dogs by Griffin and colleagues in 1979. [2] [3] DLE is one form of cutaneous lupus erythematosus (CLE). DLE occurs in dogs in two forms: a ...
Lupus is a chronic disease that can cause inflammation and pain in any part of the body. The disease impacts about 1.5 million Americans, but women are nine times more likely to develop lupus than ...
This type of cancer is common in some dog breeds. Dogs that only have surgery usually live less than a year, and if the cancer is already advanced at the time of diagnosis, the survival time is ...
Dogs suffering from autoimmune diseases of the skin may experience a variety of symptoms, including persistent itching and scratching, lesions, wounds, blisters, and other skin damage, as well as loss of skin pigment. [5] Two cases of autoimmune diseases that are often found include Discoid lupus erythematosus (DLE) and Pemphigus.
Diabetes mellitus, Cushing's syndrome, Addison's disease, and hypothyroidism are the most common endocrine diseases. Immune-mediated hemolytic anemia is a devastating disease that causes severe anemia in dogs through red blood cell destruction by the immune system.
The modern period, beginning in 1920, saw major developments in research into the cause and treatment of discoid and systemic lupus. Research conducted in the 1920s and 1930s led to the first detailed pathologic descriptions of lupus and demonstrated how the disease affected the kidney, heart, and lung tissue. [ 165 ]