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2. Diphenhydramine - Wikipedia

   en.wikipedia.org/wiki/Diphenhydramine

   Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative. It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects. [11] [2] Diphenhydramine is also a potent anticholinergic. [12]

3. Clemastine - Wikipedia

   en.wikipedia.org/wiki/Clemastine

   Clemastine, also known as meclastin, is a first-generation H1 histamine antagonist (antihistamine) with anticholinergic properties (drying) and sedative side effects. [1] Like all first-generation antihistamines, it is sedating. [2] [3] Patented in 1960, it came into medical use in 1967. [4]

4. Brompheniramine - Wikipedia

   en.wikipedia.org/wiki/Brompheniramine

   Brompheniramine, sold under the brand name Dimetapp among others, is a first-generation antihistamine drug of the propylamine (alkylamine) class. [2] It is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.

5. Cyproheptadine - Wikipedia

   en.wikipedia.org/wiki/Cyproheptadine

   Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It was patented in 1959 and came into medical use in 1961. [5]

6. Doxylamine - Wikipedia

   en.wikipedia.org/wiki/Doxylamine

   Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7] [4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.

7. Which Allergy Medicine Is Actually Most Effective? - AOL

   www.aol.com/lifestyle/allergy-medicine-actually...

   Claritin is a brand name for loratadine. Like Zyrtec, this is a second-generation antihistamine. “The second generation drugs do not pass as readily into the brain and are less sedating,” Dr ...