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Hypertrophic Osteodystrophy (HOD) is a bone disease that occurs most often in fast-growing large and giant breed dogs; however, it also affects medium breed animals like the Australian Shepherd. The disorder is sometimes referred to as metaphyseal osteopathy , and typically first presents between the ages of 2 and 7 months. [ 1 ]
In the central nervous system (CNS), glia suppress repair. Glial cells known as astrocytes enlarge and proliferate to form a scar and produce inhibitory molecules that inhibit regrowth of a damaged or severed axon. In the peripheral nervous system (PNS), glial cells known as Schwann cells (or also as neuri-lemmocytes) promote repair. After ...
Knee joint of dog. Piece showing knee joint of dog. An untreated hygroma can develop into a large swelling that stresses the surrounding skin and becomes an open wound with the possibility of infection that is much more difficult to treat. In most cases, a hygroma is a single occurrence for an animal, but other individuals will have repeated ...
Endogenous regeneration in the brain is the ability of cells to engage in the repair and regeneration process. While the brain has a limited capacity for regeneration, endogenous neural stem cells, as well as numerous pro-regenerative molecules, can participate in replacing and repairing damaged or diseased neurons and glial cells.
Gliogenesis results in the formation of non-neuronal glia populations from neuronal cells. In this capacity, glial cells provide multiple functions to both the central nervous system (CNS) and the peripheral nervous system (PNS). Subsequent differentiation of glial cell populations results in function-specialized glial lineages.
Pituitary gland tumors are very common in the canine. A productive form arising from the anterior pituitary is the primary cause of Cushing's disease of dogs. This tumor causes excessive production of cortisol from the adrenal cortex which leads to the classic signs of alopecia (hair loss), polyuria (excessive urination), polydipsia (excessive water drinking), and a pot-bellied appearance of ...
Panosteitis, sometimes shortened to pano among breeders, [1] is an occasionally seen long bone condition in large breed dogs.It manifests with sudden, unexplained pain and lameness that may shift from leg to leg, usually between 5 and 14 months of age, earning the nickname "growing pains. "[2] Signs such as fever, weight loss, anorexia, and lethargy can also be seen.
While small dogs and cats can survive comfortably with three legs, larger dogs, horses, and farm animals require the limb to support their weight. Surgery has also been done on birds that are used for breeding purposes. Each prosthetic limb is custom-made to fit the individual needs of the specific animal. [13] [14] [15]
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