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In people with smear-positive pulmonary TB (without HIV co-infection), after 5 years without treatment, 50–60% die while 20–25% achieve spontaneous resolution (cure). TB is almost always fatal in those with untreated HIV co-infection and death rates are increased even with antiretroviral treatment of HIV. [168]
Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB.. The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months.
Miliary tuberculosis is a form of tuberculosis that is characterized by a wide dissemination into the human body and by the tiny size of the lesions (1–5 mm). Its name comes from a distinctive pattern seen on a chest radiograph of many tiny spots distributed throughout the lung fields with the appearance similar to millet seeds—thus the term "miliary" tuberculosis.
6 to 9H 2 — An intermittent twice-weekly regimen for the above two treatment regimens is an alternative if administered under Directly observed therapy (DOT). 4R — rifampicin for 4 months is an alternative for those who are unable to take isoniazid or who have had known exposure to isoniazid-resistant TB.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
[2] Those with HIV and TB are more likely to have disseminated TB (where TB spreads to the bloodstream or to other organs outside the lungs). The most common sites of extrapulmonary TB in those with HIV are the lymph nodes, liver, spleen, and central nervous system (TB meningitis). [2] TB meningitis in those with HIV has a mortality rate of 40% ...
Successful diagnosis of XDR-TB depends on the patient's access to quality health-care services. If TB bacteria are found in the sputum, the diagnosis of TB can be made in a day or two, but this finding will not be able to distinguish between drug-susceptible and drug-resistant TB. To evaluate drug susceptibility, the bacteria need to be ...
The regimen consists of initial two months' intensive therapy with isoniazid, rifampicin, ethambutol and pyrazinamide followed by a six to twelve month course of isoniazid and rifampicin. [13] [14] Almost all the patients respond to medical therapy. Surgery is limited in curetting the bone cavities to promote early healing in cystic tuberculosis.