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The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
The 2002 Women's Health Initiative of the National Institutes of Health found disparate results for all cause mortality with hormone replacement, finding it to be lower when HRT was begun earlier, between age 50–59, but higher when begun after age 60.
[9] [8] As such, it is an estrogen, or an agonist of the estrogen receptors. [8] [9] Estradiol acetate is of about 15% higher molecular weight than estradiol due to the presence of its C3 acetate ester. [3] Because estradiol acetate is a prodrug of estradiol, it is considered to be a natural and bioidentical form of estrogen. [9] [10]
In 2000, more than one in five women over 50 were taking hormones, according to statistics tracked by the Menopause Society, an influential health-care nonprofit. By 2008, fewer than 5 percent of ...
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[126] [127] [124] Women who are not on a birth control pill or hormone therapy have a risk of VTE of about 1 to 5 out of 10,000 women per year. [126] [127] [116] [124] In women taking a birth control pill containing ethinylestradiol and a progestin, the risk of VTE is in the range of 3 to 10 out of 10,000 women per year.
Topical estrogen creams have been touted as a solution to skin aging due to menopause for decades— but they may not be right for you. Skip to main content. 24/7 Help. For premium support please ...
For women already taking the medication, it can be used to treat osteoporosis, although it is not recommended solely for this use. [21] Some lesser known uses are as a means of high-dose estrogen therapy in the treatment of breast cancer in both women and men and in the treatment of prostate cancer in men.