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Arachnoid granulations (also arachnoid villi, and pacchionian granulations or bodies) are small outpouchings of the arachnoid mater and subarachnoid space into the dural venous sinuses of the brain. The granulations are thought to mediate the draining of cerebrospinal fluid (CSF) from the subarachnoid space into the venous system .
The dural venous sinuses (also called dural sinuses, cerebral sinuses, or cranial sinuses) are venous sinuses (channels) found between the periosteal and meningeal layers of dura mater in the brain. [ 1 ] [ 2 ] They receive blood from the cerebral veins , and cerebrospinal fluid (CSF) from the subarachnoid space via arachnoid granulations .
The arachnoid mater makes arachnoid villi, small protrusions through the dura mater into the venous sinuses of the brain, which allow CSF to exit the subarachnoid space and enter the blood stream. Unlike the dura mater, which receives a rich vascular supply from numerous arteries, the arachnoid mater is avascular (lacking blood vessels).
The fluid then flows around the superior sagittal sinus to be reabsorbed via the arachnoid granulations (or arachnoid villi) into the venous sinuses, after which it passes through the jugular vein and major venous system.
CSF returns to the vascular system by entering the dural venous sinuses via arachnoid granulations. [2] These are outpouchings of the arachnoid mater into the venous sinuses around the brain, with valves to ensure one-way drainage. [2] This occurs because of a pressure difference between the arachnoid mater and venous sinuses. [3]
The superior sagittal sinus (also known as the superior longitudinal sinus), within the human head, is an unpaired dural venous sinus lying along the attached margin of the falx cerebri. It allows blood to drain from the lateral aspects of the anterior cerebral hemispheres to the confluence of sinuses .
Generally, people describe a sinus headache as a feeling of facial pain or pressure in the sinus area that might radiate to the rest of the head. "People typically talk about it like a pressure ...
The meningeal lymphatic system is composed of a network of vessels along the dural sinus in the dura which express lymphatic endothelial cell marker proteins, including PROX1, LYVE1, and PDPN. The vessels extend along the length of both the superior sagittal and transverse sinuses and directly connects to the deep cervical lymph nodes. [ 1 ]