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o-Toluidine is absorbed through inhalation and dermal contact as well as from the gastrointestinal tract. [19] [13] [20] [21]The metabolism of o-toluidine involves many competing activating and deactivating pathways, including N-acetylation, N-oxidation, and N-hydroxylation, and ring oxidation.
2-Nitrotoluene or ortho-nitrotoluene is an organic compound with the formula CH 3 C 6 H 4 NO 2. It is pale yellow liquid that crystallizes in two forms, called α (−9.27 °C) and β (−3.17 °C). It is mainly a precursor to o-toluidine, which is an intermediate in the production of various dyes. [4]
The principal application involves its sulfonation to give the 4-nitrotoluene-2-sulfonic acid (with the –SO 3 H group adjacent to methyl). This species can be oxidatively coupled to produce stilbene derivatives, [10] which are used as dyes. [11]
A laboratory route to 2- and 4-chlorotoluene proceeds from 2- and 4-toluidines (i.e. 2- and 4-aminotoluene). These compounds are diazotized followed by treatment with cuprous chloride. [1] Industrially, the diazonium method is reserved for 3-chlorotoluene. The industrial route to 2- and 4-chlorotoluene entails direct reaction of toluene with ...
Mononitrotoluene or nitrotoluene (MNT or NT), is any of three organic compounds with the formula C 6 H 4 (CH 3)(NO 2). [1] They can be viewed as nitro derivatives of toluene or as methylated derivatives of nitrobenzene. Mononitrotoluene comes in three isomers, differing by the relative position of the methyl and nitro groups. All are pale ...
2,4-Dinitrotoluene; M. Mononitrotoluene; N. 2-Nitrotoluene; 3-Nitrotoluene; 4-Nitrotoluene This page was last edited on 30 January 2024, at 19:32 ...
The three isomers of nitrobenzoic acid are: 2-Nitrobenzoic acid is prepared by oxidation of 2-nitrotoluene.; 3-Nitrobenzoic acid is a precursor to 3-aminobenzoic acid, which in turn is used to prepare some dyes.
Free radical nitration of alkanes. [4] The reaction produces fragments from the parent alkane, creating a diverse mixture of products; for instance, nitromethane, nitroethane, 1-nitropropane, and 2-nitropropane are produced by treating propane with nitric acid in the gas phase (e.g. 350–450 °C and 8–12 atm).
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