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4) Epothilones, mainly ixabepilone, are relatively new drugs that can be used to treat non-small lung, ovarian, and prostate cancers. [3] Epothilones cause microtubule disruption (like taxane-based drugs), which impairs axonal transport and leads to hyperexcitability of peripheral neurons.
If the disease is associated with cancer, direct treatment of the cancer often relieves the symptoms of LEMS. Other treatments often used are steroids , azathioprine , which suppress the immune system, intravenous immunoglobulin , which outcompetes autoreactive antibody for Fc receptors, and pyridostigmine and 3,4-diaminopyridine , which ...
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Like other medications for the treatment of (ED), Cialis — and its generic version, tadalafil — can cause adverse effects at first. Fortunately, most tadalafil side effects are mild and ...
Neuromyotonia causes antibodies to damage the normal function of potassium rectifier channels, while Lambert–Eaton syndrome causes antibodies to attack presynaptic calcium channels.(reference 7) Congenital myasthenia gravis is a large group of diseases, since the genetic defects can affect any point in the chain of events leading to ...
Credit - Getty Images. B reast cancer is not a single disease but multiple ones, each carrying varying degrees of risk for endangering women’s health.. In recent years, many researchers have ...
A Brazilian woman who developed massive tumors on her legs caused by a rare genetic disorder has already undergone several surgeries to remove the growths but said it has damaged her relationships ...
The vascular (blood) system can be affected by solid tumors. Between 15 and 25 percent of deep vein thrombosis is caused by cancer (often by a tumor compressing a vein), and it may be the first hint that cancer is present. It causes swelling and pain in the legs, especially the calf, and (rarely) in the arms. [19]