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Glibenclamide, also known as glyburide, is an antidiabetic medication used to treat type 2 diabetes. [1] It is recommended that it be taken together with diet and exercise. [1] It may be used with other antidiabetic medication. [1] It is not recommended for use by itself in type 1 diabetes. [1] It is taken by mouth. [1]
Gliclazide, sold under the brand name Diamicron among others, is a sulfonylurea type of anti-diabetic medication, used to treat type 2 diabetes. [7] It is used when dietary changes, exercise, and weight loss are not enough. [4] It is taken by mouth. [7] Side effect may include low blood sugar, vomiting, abdominal pain, rash, and liver problems.
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The primary side-effect is hypoglycemia, which appears to happen more commonly with sulfonylureas than with other treatments. [ 27 ] A Cochrane systematic review from 2011 showed that treatment with Sulfonylureas did not improve control of glucose levels more than insulin at 3 nor 12 months of treatment. [ 28 ]
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The long-term study is comparing the long-term benefits and risks of four widely used diabetes drugs in combination with metformin, the most common first-line drug for treating type 2 diabetes. The study will compare drug effects on glucose levels, adverse effects, diabetes complications and quality of life over an average of nearly five years ...
Again, this isn't a common side effect. But if you’re experiencing negative mood or personality changes (or any other Ozempic side effects ), talk to your doctor ASAP, say both experts.