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This breed of rat was first produced by the Sprague Dawley farms (later to become the Sprague Dawley Animal Company) in Madison, Wisconsin, in 1925. The name was originally hyphenated, although the brand styling today (Sprague Dawley, the trademark used by Inotiv) is not. The average litter size of the Sprague Dawley rat is 11.0. [29]
Sprague Dawley rat; W. Wistar rat; Z. ZDF rat; Zucker diabetic fatty rat; Zucker rat This page was last edited on 12 October 2015, at 22:02 (UTC). Text is available ...
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The company began offering rats in 1969, including Sprague Dawley, one of the most popular breeds of laboratory rats. That same year, Taconic became the first breeder to receive full accreditation from the American Association for the Accreditation of Laboratory Animals. [citation needed]
Harlan UK Ltd. is the British arm of Harlan Sprague Dawley Inc. It has an annual turnover of £6.6 million, according to the British Union for the Abolition of Vivisection (BUAV). [6] The company supplies marmosets, beagles, cats, rabbits, guinea pigs, rats, mice, gerbils, and hamsters, as well as hybrid, mutant, and transgenic animals.
Sprague-Dawley rats have a lifespan of about two years and have a high risk of cancer over their lifespan (one study concluded that over eighty percent of males and over seventy percent of females developed cancer under normal conditions). [40] [41] [42] The Séralini experiment covered the normal lifespan of these rats. The longer an ...
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"The period before World War I led to the initiation of inbreeding in rats by Dr Helen King in about 1909 and in mice by Dr C. C. Little in 1909. The latter project led to the development of the DBA strain of mice, now widely distributed as the two major sub-strains DBA/1 and DBA/2, which were separated in 1929-1930.