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  2. Lexapro: Everything You Need to Know About Its Side Effects - AOL

    www.aol.com/lexapro-everything-know-side-effects...

    Fatigue or drowsiness. Dry mouth. Intimate side effects. There’s also a connection between Lexapro and weight — some people experience weight gain, while others may see weight loss as a side ...

  3. Escitalopram (Lexapro): Everything You Need to Know Before ...

    www.aol.com/escitalopram-lexapro-everything-know...

    Lexapro is one of the most recognizable drug names of our modern era. Escitalopram, a less recognizable term, is the generic name for this common prescription antidepressant.

  4. Mysterious 'Brain Zaps' Are Being Reported By Lexapro ... - AOL

    www.aol.com/mysterious-brain-zaps-being-reported...

    Lexapro, for example, is also commonly associated with brain zaps—but just because you take one of these meds does not mean you’re guaranteed to develop the side effect when you stop taking it.

  5. Escitalopram - Wikipedia

    en.wikipedia.org/wiki/Escitalopram

    Escitalopram, sold under the brand names Lexapro and Cipralex, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [9] Escitalopram is mainly used to treat major depressive disorder and generalized anxiety disorder. [9] It is taken by mouth, [9] available commercially as an oxalate salt exclusively.

  6. First pass effect - Wikipedia

    en.wikipedia.org/wiki/First_pass_effect

    Illustration showing the hepatic portal vein system. The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.

  7. Drug delivery to the brain - Wikipedia

    en.wikipedia.org/wiki/Drug_delivery_to_the_brain

    It also can work to mask the drug peptide from peptide-degrading enzymes in the brain [7] Also a "targetor" molecule could be attached to the drug that helps it pass through the barrier and then once inside the brain, is degraded in such a way that the drug cannot pass back through the brain. Once the drug cannot pass back through the barrier ...

  8. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

    www.aol.com/switching-antidepressants-safety...

    One of the safer techniques simply reduces your current dosage to a complete stop, then waits for it to clear your body before starting the new antidepressant. You may need to use this technique ...

  9. Serotonin–norepinephrine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    Formation of norepinephrine is reduced by autoreceptors through the rate-limiting enzyme tyrosine hydroxylase, an effect mediated by decreased cyclic AMP-mediated phosphorylation-activation of the enzyme. [29] α 2 receptors also cause decreased intracellular cyclic AMP expression which results in smooth muscle relaxation or decreased secretion ...