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  2. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors ...

  3. Sodium/glucose cotransporter 2 - Wikipedia

    en.wikipedia.org/wiki/Sodium/glucose_cotransporter_2

    SGLT2 is a member of the sodium glucose cotransporter family, which are sodium-dependent glucose transport proteins. SGLT2 is the major cotransporter involved in glucose reabsorption in the kidney. [6] SGLT2 is located in the early proximal tubule, and is responsible for reabsorption of 80-90% of the glucose filtered by the kidney glomerulus. [7]

  4. Type 2 diabetes drugs could lower dementia, Parkinson's ... - AOL

    www.aol.com/type-2-drugs-could-lower-133000670.html

    “SGLT2 inhibitors reduce common risk factors associated with dementia and Parkinson’s disease, such as hyperglycemia, insulin resistance, obesity, hypertension, and heart failure. These ...

  5. Dapagliflozin - Wikipedia

    en.wikipedia.org/wiki/Dapagliflozin

    Dapagliflozin is used along with diet, exercise, and usually with other glucose-lowering medications, to improve glycaemic control in adults with type 2 diabetes. . Dapagliflozin, in addition to other SGLT2-inhibitors, was shown to reduce the rate of decline in kidney function and kidney failure in non-diabetic and type 2 diabetic adults when added to the existing treatment

  6. Drugs like Ozempic may help lower 2nd stroke, heart attack risk

    www.aol.com/drugs-ozempic-may-help-lower...

    A new study says that type 2 diabetes medications GLP-1 agonists and SGLT2 inhibitors may help lower a stroke survivor’s risk of experiencing a subsequent stroke, heart attack, or death ...

  7. Sodium-glucose transport proteins - Wikipedia

    en.wikipedia.org/wiki/Sodium-glucose_transport...

    SGLT2 inhibitors, also called gliflozins, [14] are used in the treatment of type 2 diabetes. SGLT2 is only found in kidney tubules and in conjunction with SGLT1 resorbs glucose into the blood from the forming urine. By inhibiting SGLT2, and not targeting SGLT1, glucose is excreted which in turn lowers blood glucose levels.

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