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Summation, which includes both spatial summation and temporal summation, is the process that determines whether or not an action potential will be generated by the combined effects of excitatory and inhibitory signals, both from multiple simultaneous inputs (spatial summation), and from repeated inputs (temporal summation).
The definition above is spatial summation (which they pictured as having multiple synapses placed close together, so that the effect of their firing sums up). By "temporal summation" they meant that the total incoming signal is ∑ τ = 0 T ∑ j = 1 n w i j ( t ) N j ( t − τ ) {\displaystyle \sum _{\tau =0}^{T}\sum _{j=1}^{n}w_{ij}(t)N_{j ...
Spatial summation occurs when postsynaptic potentials from adjacent synapses on the cell occur simultaneously and add together. An action potential occurs when the summated EPSPs, minus the summated IPSPs, in an area of membrane reach the cell's threshold potential.
Temporal summation refers to successive excitatory stimuli on the same location of the postsynaptic neuron. Both types of summation are the result of adding together many excitatory potentials; the difference being whether the multiple stimuli are coming from different locations at the same time (spatial) or at different times from the same ...
Spatial summation means that the effects of impulses received at different places on the neuron add up, so that the neuron may fire when such impulses are received ...
Postsynaptic potentials undergo spatial and temporal summation due to their graded nature. [9] Spatial summation: When inputs are received simultaneously at nearby synapses, their postsynaptic potentials combine. Multiple excitatory inputs combine resulting in greater membrane depolarization (more positive).
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Therefore, in order to achieve threshold and generate an action potential, the postsynaptic neuron has the capacity to add up all of the incoming EPSPs based on the mechanism of summation, which can occur in time and space. Temporal summation occurs when a particular synapse is stimulated at a high frequency, which causes the postsynaptic ...