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The juxtaglomerular apparatus is part of the kidney nephron, next to the glomerulus. It is found between afferent arteriole and the thick ascending limb of the loop of Henle (distal straight tubule) of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. [2] [3]
Within the nephron of the kidney, the ascending limb of the loop of Henle is a segment of the heterogenous loop of Henle downstream of the descending limb, after the sharp bend of the loop. This part of the renal tubule is divided into a thin and thick ascending limb ; the thick portion is also known as the distal straight tubule , in contrast ...
In other words, a juxtamedullary nephron is a nephron whose renal corpuscle is near the medulla, and whose proximal convoluted tubule and its associated loop of Henle occur deeper in the medulla than the other type of nephron, the cortical nephron. The juxtamedullary nephrons comprise only about 15% of the nephrons in the human kidney.
Diagram showing the basic physiologic mechanisms of the kidney. The kidney's ability to perform many of its functions depends on the three fundamental functions of filtration, reabsorption, and secretion, whose sum is called renal clearance or renal excretion. That is: Urinary excretion rate = Filtration rate – Reabsorption rate + Secretion ...
Like reptiles, birds have a renal portal system, but it does not deliver blood to the loops of Henle, blood is delivered only to the proximal and distal tubules of the nephrons. When birds are in a state of dehydration , nephrons without a loop of Henle stop filtering, while nephrons with a loop continue, but due to the presence of a loop, they ...
The kidney is well supplied with lymphatic vessels, [114] which remove excess fluid with substances and macromolecules dissolved in it from the interstitium that fills the space between the tubules and blood vessels. [115] [116] The anatomy of the lymphatic system of the kidney is similar between mammals. [117]
Diagram of the circulation related to a single glomerulus, associated tubule, and collecting system The renal corpuscle in the cortex (outer layer) of the kidney. At the top, the renal corpuscle containing the glomerulus. The filtered blood exits into the renal tubule as filtrate, at right. At left, blood flows from the afferent arteriole (red ...
The collecting duct system of the kidney consists of a series of tubules and ducts that physically connect nephrons to a minor calyx or directly to the renal pelvis.The collecting duct participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and vasopressin (antidiuretic hormone).