Search results
Results from the WOW.Com Content Network
The persistent radical effect (PRE) in chemistry describes and explains the selective product formation found in certain free-radical cross-reactions. In these type of reactions, different radicals compete in secondary reactions. The so-called persistent (long-lived) radicals do not self-terminate and only react in cross-couplings.
Organic reactions can be organized into several basic types. Some reactions fit into more than one category. For example, some substitution reactions follow an addition-elimination pathway. This overview isn't intended to include every single organic reaction. Rather, it is intended to cover the basic reactions.
The Kharasch addition is an organic reaction and a metal-catalysed free radical ... An example of Kharasch addition is the synthesis of 1,1,3-trichloro-n ...
Radical initiators are utilized in industrial processes such as polymer synthesis. Typical examples are molecules with a nitrogen-halogen bond, azo compounds , and organic and inorganic peroxides . [ 2 ]
Large excesses of activated alkenes can be used to intercept the alkyl radical and results in formation of a C-C bond from an unactivated C-H bond. [21] In the presence of oxygen, the alkyl radical is trapped and forms an organic peroxy radical. This intermediate is trapped by the nitrosyl radical and then isomerizes to give a δ-nitrate ester ...
In organic chemistry, the Michael reaction or Michael 1,4 addition is a reaction between a Michael donor (an enolate or other nucleophile) and a Michael acceptor (usually an α,β-unsaturated carbonyl) to produce a Michael adduct by creating a carbon-carbon bond at the acceptor's β-carbon.
The high reactivity of free radical species renders radical-based synthetic approaches decidedly suitable for cascade reactions. [4] One of the most widely recognized examples of the synthetic utility of radical cascades is the cyclization sequence employed in the total synthesis of (±)-hirsutene, in 1985 (Scheme 6).
Radical elimination can be viewed as the reverse of radical addition. In radical elimination, an unstable radical compound breaks down into a spin-paired molecule and a new radical compound. Shown below is an example of a radical elimination reaction, where a benzoyloxy radical breaks down into a phenyl radical and a carbon dioxide molecule. [7]