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Ketoconazole has been used to treat eumycetoma but has many side effects. [25] Actinomycetes usually respond well to medical treatment, but eukaryotic infections are generally resistant and may require surgical interventions including salvage procedures as bone resection or even the more radical amputation.
Laser treatment of drusen has been studied. While it is possible to eliminate drusen with this treatment strategy, it has been shown that this fails to reduce the risk of developing the choroidal neovascularisation which causes the blindness associated with age-related macular degeneration. [15]
As such, portions of the diseased tissue may be left in the foot after surgery. Inadequate excision is the leading cause of recurrence. [2] [7] Radiotherapy has been shown to reduce the size of the nodules and reduce the pain associated with them. It is approximately 80% effective, with minimal side effects. [11]
Patients usually lose the ability to ambulate 10 – 20 years after symptoms appear. [3] Milder forms present with symptoms other than weakness, such as muscle aches, cramps, or exercise intolerance, and people in this group can retain ambulation beyond age 60. [ 3 ]
There is currently no known pharmacological treatment to hereditary motor and sensory neuropathy. However, the majority of people with these diseases are able to walk and be self-sufficient. [3] Some methods of relief for the disease include physical therapy, stretching, braces, and sometimes orthopedic surgery.
Recently, central serous chorioretinopathy has been understood to be part of the pachychoroid spectrum. [5] [6] In pachychoroid spectrum disorders, of which CSR represents stage II, the choroid, the highly vascularized layer below the retina, is thickened and congested with increased blood vessel diameter, especially in the deep choroid (the so-called Haller's layer).
Signs and symptoms of peroneal nerve palsy are related to mostly lower legs and foot which are the following: [3] Decreased sensation, numbness, or tingling in the top of the foot or the outer part of the upper or lower leg; Foot drops (unable to hold the foot straight across) Toes drag while walking; Weakness of the ankles or feet; Prickling ...
A patient recovering from surgery to treat foot drop, with limited plantar and dorsiflexion.. Foot drop is a gait abnormality in which the dropping of the forefoot happens out of weakness, irritation or damage to the deep fibular nerve (deep peroneal), including the sciatic nerve, or paralysis of the muscles in the anterior portion of the lower leg.