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The chief and parietal cells produce and secrete mucus (F) to protect the lining of the stomach (C) against the harsh pH of stomach acid. The mucus is basic, while the stomach acid (A) is acidic. In the human digestive system, mucus is used as a lubricant for materials that must pass over membranes, e.g., food passing down the esophagus.
The mucosa is composed of one or more layers of epithelial cells that secrete mucus, and an underlying lamina propria of loose connective tissue. [1] The type of cells and type of mucus secreted vary from organ to organ and each can differ along a given tract. [2] [3]
Pepsin is a protease that can digest and damage stomach cells. To prevent these disastrous effects, mucus and bicarbonate ions (HCO 3 −) are secreted by the foveolar cells. The mucus allows the acid at pH above 4 to penetrate lining, but below pH 4 (i.e. when acid is more concentrated) the acid cannot penetrate the mucus.
Alkaline mucus exists in the human eye, stomach, saliva, and cervix. [5] In the stomach, alkaline mucus is secreted by gastric glands in the gastric mucosa of the stomach wall. [6] Secretion of alkaline mucus is necessary to protect the mucous membrane of the stomach from acids released during digestion. [6]
They secrete a purely serous fluid that begins lipid hydrolysis. They also facilitate the perception of taste through secretion of digestive enzymes and proteins. [ 12 ] The arrangement of these glands around the circumvallate papillae provides a continuous flow of fluid over the great number of taste buds lining the sides of the papillae, and ...
Control your cough. Coughing is a physiologic way to rid one of some of the congestion, says Amesh A. Adalja, M.D., senior scholar at the Johns Hopkins Center for Health Security. Controlled cough ...
The first cells of all of the glands are mucus-secreting foveolar cells that line the gastric pits. The mucus produced here is less acidic than that produced by the mucous neck cells. Fundic glands found in the fundus and also in the body have another two cell types–gastric chief cells and parietal cells (oxyntic cells).
May Cause Alcohol Dependence “Regular or excessive alcohol consumption can lead to alcohol-related problems, including addiction, liver damage, and increased risk of certain cancers,” says ...