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Vitamin D and Omega-3 Trial (VITAL) [1] was a clinical trial designed to investigate the use of daily dietary supplements of vitamin D and fish oil.. The sponsor of the study was Brigham and Women's Hospital, collaborating with The National Cancer Institute, National Heart, Lung, and Blood Institute, Office of Dietary Supplements, National Institute of Neurological Disorders and Stroke ...
Vitamin D is a group of structurally related, fat-soluble compounds responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, along with numerous other biological functions. [1] [2] In humans, the most important compounds within this group are vitamin D 3 (cholecalciferol) and vitamin D 2 (ergocalciferol). [2] [3]
In 1969 he determined that vitamin D receptors (VDR) were present in the intestine. [3] In 1971 the Norman laboratory reported the chemical structure of the active form of vitamin D to be 1,25-dihydroxycholecalciferol (which is also known as 1α,25-dihydroxyvitamin D3, and 1α,25-(OH) 2 D 3). [4]
Pre-eclampsia: There has been an association between vitamin D deficiency and women who develop pre-eclampsia in pregnancy. The exact relationship of these conditions is not well understood. [17] Maternal vitamin D deficiency may affect the baby, causing overt bone disease from before birth and impairment of bone quality after birth. [9] [18]
Vitamin D supplements may have no bearing on the severity of injuries from falls in postmenopausal women and older men, according to a new draft recommendation. Vitamin D may not prevent fractures ...
However, studies have looked at how supplementation—including vitamin D, fish-oil derived omega 3s, and HMB—might help preserve or build muscle, in general, according to a 2017 review in ...
One common active form is 1,25-dihydroxyvitamin D. [4] The term vitamin D in this article means cholecalciferol, ergocalciferol, 25-hydroxyvitamin D, and the active forms. The role of vitamin D is best characterized as enabling calcium absorption and regulating calcium homeostasis. Vitamin D also play a role in phosphate absorption. [5]
Just like any other vitamin, you want to be sure you're getting enough Vitamin D, but you also don't want too much. You know what they say: It is possible to have too much of a good thing!