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A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Dendrobium alkaloids are natural products and so-called pseudoalkaloids. [1] Occurrence. Dendrobium alkaloids are found in the genus Dendrobium, particularly in ...
While dendrobine's effects on humans have not been studied extensively, studies of its pharmacological effects on various small animals were conducted in 1935 by Chen and Chen. [2] It was concluded that dendrobine exhibited a weak analgesic effect when administered to mice (5–15 mg/kg), and an antipyretic effect when administered to rabbits ...
Additionally, the medicinal use of cannabidiol, or CBD, often formulated as oil—which is made from cannabis plants but has low levels of their primary psychoactive element, THC—is allowed in ...
[6] [7] The CB 1 receptor is expressed mainly in the brain (central nervous system or "CNS"), but also in the lungs, liver and kidneys. The CB 2 receptor is expressed mainly in the immune system, in hematopoietic cells, [8] and in parts of the brain. [9] The protein sequences of CB 1 and CB 2 receptors are about 44% similar.
CBN was the first cannabis compound to be isolated from cannabis extract in the late 1800s. Its structure and chemical synthesis were achieved by 1940 [34], followed by some of the first pre-clinical research studies to determine the effects of individual cannabis-derived compounds in vivo. [35]
A 2005 meta analysis concluded that adolescent use of cannabis increases the risk of psychosis, and that the risk is dose-related. [48] A 2004 literature review on the subject concluded that cannabis use is associated with a two-fold increase in the risk of psychosis, but that cannabis use is "neither necessary nor sufficient" to cause ...
More than one in five people age 50 or older have used cannabis at least once in the past year, a new survey reveals. And most of them smoke, consume or vape cannabis products once or twice a ...