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Mitragyna speciosa is a tropical evergreen tree of the Rubiaceae family (coffee family) native to Southeast Asia. [3] It is indigenous to Cambodia, Thailand, Indonesia, Malaysia, Myanmar, and Papua New Guinea, [4] where its leaves, known as "kratom" have been used in herbal medicine since at least the 19th century. [5]
People report using kratom for a variety of reasons, including pain relief, fatigue and to help curb drug withdrawal symptoms, according to the National Institute on Drug Abuse.
Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. [4] It is an opioid that is typically consumed as a part of kratom for its pain-relieving and euphoric effects.
7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa, commonly known as kratom. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
Pain relief creams work by delivering active ingredients directly to the affected area. These ingredients can create sensations like cooling, warming, or numbing, which distract from pain signals ...
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Mitragynine pseudoindoxyl is a μ-opioid receptor agonist and δ-opioid receptor antagonist.It is a G protein biased agonist at the μ-opioid receptor, which may be responsible for its favorable side effect profile compared to conventional opioids. [3]
The white and red versions of Haw Par Tiger Balm. Tiger Balm (Chinese: 虎 標 萬 金 油; pinyin: Hǔbiao Wànjīnyóu; Pe̍h-ōe-jī: Hó͘-phiau Bān-kim-iû) is an analgesic heat rub manufactured and distributed by Singaporean company Haw Par Healthcare. It is used for external pain relief.