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Oleoylethanolamide (OEA) is an endogenous peroxisome proliferator-activated receptor alpha (PPAR-α) agonist.It is a naturally occurring ethanolamide lipid that regulates feeding and body weight in vertebrates ranging from mice to pythons.
Oleylamine is an organic compound with a molecular formula C 18 H 35 NH 2. [1] It is an unsaturated fatty amine related to the fatty acid oleic acid . The pure compound is a clear and colorless liquid.
As an organic compound, phenylethanolamine is a β-hydroxylated phenethylamine that is also structurally related to a number of synthetic drugs in the substituted phenethylamine class. In common with these compounds, phenylethanolamine has strong cardiovascular activity [ 1 ] and, under the name Apophedrin , has been used as a drug to produce ...
Oleamide has been found in Ziziphus jujuba, also known as Jujube fruit. [14]Synthetic oleamide has a variety of industrial uses, including as a lubricant. [15]Oleamide was found to be leaching out of polypropylene plastics in laboratory experiments, affecting experimental results. [16]
Hydroxyethyl cellulose is a gelling and thickening agent derived from cellulose. It is widely used in cosmetics, cleaning solutions, and other household products. [ 1 ] Hydroxyethyl cellulose and methyl cellulose are frequently used with hydrophobic drugs in capsule formulations, to improve the drugs' dissolution in the gastrointestinal fluids.
Everolimus, sold under the brand name Afinitor among others, is a medication used as an immunosuppressant to prevent rejection of organ transplants [10] and as a targeted therapy in the treatment of renal cell cancer and other tumours. [11] This compound also has a use in cardiovascular drug-eluting stent technologies to inhibit restenosis.
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SM-102 is a synthetic amino lipid which is used in combination with other lipids to form lipid nanoparticles. [1] These are used for the delivery of mRNA-based vaccines, [2] [3] [4] and in particular SM-102 forms part of the drug delivery system for the Moderna COVID-19 vaccine.