Search results
Results from the WOW.Com Content Network
Doses of oral polio vaccine are added to sugar cubes for use in a 1967 vaccination campaign in Bonn, West Germany. During the race to develop an oral polio vaccine, several large-scale human trials were undertaken. By 1958, the National Institutes of Health had determined that OPV produced using the Sabin strains was the safest. [43]
The history of polio (poliomyelitis) infections began during prehistory. Although major polio epidemics were unknown before the 20th century, [1] the disease has caused paralysis and death for much of human history. Over millennia, polio survived quietly as an endemic pathogen until the 1900s when major epidemics began to occur in Europe. [1]
Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
Polio: An American Story by David M. Oshinsky, professor of history at the University of Texas at Austin, documents the polio epidemic in the United States during the 1940s and 1950s and the race to develop a vaccine, which led to 2 different types of polio vaccine: inactivated poliovirus vaccine, developed by a team led by Jonas Salk, and oral poliovirus vaccine, developed by a team led by ...
As with all medications, vaccines are continually monitored for safety, and like any medication, vaccines can cause side effects. The side effects of vaccination are typically minor and go away within a few days. There is a risk that the child could have a severe allergic reaction, but these reactions are rare.
According to the U.S. Centers for Disease Control and Prevention, while "any vaccine can cause side effects", [11] most side effects are minor, primarily including sore arms or a mild fever. [11] Unlike most medical interventions vaccines are given to healthy people, where the risk of side effects is not as easily outweighed by the benefit of ...
Live, attenuated vaccines, such as smallpox and polio vaccines, are able to induce killer T-cell (T C or CTL) responses, helper T-cell (T H) responses and antibody immunity. However, attenuated forms of a pathogen can convert to a dangerous form and may cause disease in immunocompromised vaccine recipients (such as those with AIDS). While ...
Albert Sabin, a virologist who publicly disagreed with Salk and his killed vaccine, worked on creating a vaccine with live attenuated vaccines. [5] In January 1956, despite Cold War tensions, Mikhail Chumakov, the director of Moscow's Polio Research Institute, along with his wife virologist Marina Voroshilova, and his colleague Anatoli Smorodentsev, traveled to the U.S. in order to study the ...