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  2. Brain-derived neurotrophic factor - Wikipedia

    en.wikipedia.org/wiki/Brain-derived_neurotrophic...

    Brain-derived neurotrophic factor (BDNF), or abrineurin, [5] is a protein [6] that, in humans, is encoded by the BDNF gene. [ 7 ] [ 8 ] BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4 /NT-5.

  3. rs6265 - Wikipedia

    en.wikipedia.org/wiki/Rs6265

    Rs6265, also called Val66Met or G196A, is a gene variation, a single nucleotide polymorphism (SNP) in the BDNF gene that codes for brain-derived neurotrophic factor. Well over a hundred research studies have examined the polymorphism.

  4. Neurotrophic factors - Wikipedia

    en.wikipedia.org/wiki/Neurotrophic_factors

    Most neurotrophic factors belong to one of three families: (1) neurotrophins, (2) glial cell-line derived neurotrophic factor family ligands (GFLs), and (3) neuropoietic cytokines. [4] Each family has its own distinct cell signaling mechanisms , although the cellular responses elicited often do overlap.

  5. Tropomyosin receptor kinase B - Wikipedia

    en.wikipedia.org/wiki/Tropomyosin_receptor_kinase_B

    Tropomyosin receptor kinase B (TrkB), [5] [6] [7] also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans is encoded by the NTRK2 gene. [8] TrkB is a receptor for brain-derived neurotrophic factor (BDNF).

  6. Neurotrophin - Wikipedia

    en.wikipedia.org/wiki/Neurotrophin

    According to the United States National Library of Medicine's medical subject headings, the term neurotrophin may be used as a synonym for neurotrophic factor, [5] but the term neurotrophin is more generally reserved for four structurally related factors: nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). [6]

  7. Trk receptor - Wikipedia

    en.wikipedia.org/wiki/Trk_receptor

    TrkB has the highest affinity to the binding of brain-derived neurotrophic factor (BDNF) and NT-4. BDNF is a growth factor that has important roles in the survival and function of neurons in the central nervous system .

  8. Neurotrophin-4 - Wikipedia

    en.wikipedia.org/wiki/Neurotrophin-4

    78405 Ensembl ENSG00000225950 ENSMUSG00000074121 UniProt P34130 Q80VU4 RefSeq (mRNA) NM_006179 NM_001395489 NM_198190 RefSeq (protein) NP_006170 NP_937833 Location (UCSC) Chr 19: 49.06 – 49.07 Mb Chr 7: 45.06 – 45.07 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Neurotrophin-4 (NT-4), also known as neurotrophin-5 (NT-5), is a protein that in humans is encoded by the NTF4 gene ...

  9. GDNF family of ligands - Wikipedia

    en.wikipedia.org/wiki/GDNF_family_of_ligands

    The GDNF family of ligands (GFL) consists of four neurotrophic factors: glial cell line-derived neurotrophic factor (GDNF), neurturin (NRTN), artemin (ARTN), and persephin (PSPN). GFLs have been shown to play a role in a number of biological processes including cell survival, neurite outgrowth, cell differentiation and cell migration.