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Rifapentine in pregnant women has not been studied, but animal reproduction studies have resulted in fetal harm and were teratogenic. If rifapentine or rifampin are used in late pregnancy, coagulation should be monitored due to a possible increased risk of maternal postpartum hemorrhage and infant bleeding. [2]
It is part of the recommended treatment of active tuberculosis during pregnancy, though its safety in pregnancy is not known. [3] Rifampicin is of the rifamycin group of antibiotics. [3] It works by decreasing the production of RNA by bacteria. [3] Rifampicin was discovered in 1965, marketed in Italy in 1968, and approved in the United States ...
[61] [12] [62] [63] The 1994 US CDC guidelines for tuberculosis [64] erroneously cite Slutkin [63] as evidence that a nine-month regimen using only isoniazid and rifampicin is acceptable, but almost all of the patients in that study received ethambutol for the first two to three months (although this is not obvious from the abstract of that ...
Some concerns have been raised about the Xpert MTB/RIF, including operational issues and cost. The concessional price for a GeneXpert system is currently 32,000 USD for a four module instrument. As of 6 August 2012, the cost of a test cartridge in countries eligible for concessional pricing is $9.98 USD.
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the ... Rifampicin: C C Thalidomide: X X Theophylline: A C Temazepam: C X ...
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