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Antisialagogues are drugs or substances that decrease the flow rate of saliva and their effect is opposite to that of sialagogues. [1] Their origin may be both natural and synthetic. Anticholinergics generally have antisialagogue effects, and most produce some level of sedation, both being advantageous in surgical procedures. [2]
Sialometery can yield measures of stimulated salivary flow or unstimulated salivary flow. Stimulated salivary flow rate is calculated using a stimulant such as 10% citric acid dropped onto the tongue, and collection of all the saliva that flows from one of the parotid papillae over five or ten minutes. Unstimulated whole saliva flow rate more ...
It has also been defined as increased amount of saliva in the mouth, which may also be caused by decreased clearance of saliva. [ 4 ] Hypersalivation can contribute to drooling if there is an inability to keep the mouth closed or difficulty in swallowing (dysphagia) the excess saliva, which can lead to excessive spitting.
Salivary gland dysfunction affects the flow, amount, or quality of saliva produced. A reduced salivation is termed hyposalivation . Hyposalivation often results in a dry mouth condition called xerostomia , and this can cause tooth decay due to the loss of the protective properties of saliva.
Abdominal discomfort is commonly a side effect of medications as well ... They then leave the body as a bowel movement, per the U.S. National Institutes of Health. IBS can alter these processes by ...
Xerostomia, or a decrease in saliva flow, can be a side effect of many drugs, which, in turn, can lead to the development of taste disturbances such as dysgeusia. [39] Patients can lessen the effects of xerostomia with breath mints, sugarless gum, or lozenges; or physicians can increase saliva flow with artificial saliva or oral pilocarpine. [39]
Blood in saliva, vomit or urine. Cantharidin is known to cause hematemesis (vomiting of blood) and gross hematuria (blood visible in urine). It can also cause dysuria (pain while urinating). Priapism.
A study published earlier this year found that metformin can reduce feelings of hunger in people on the medication. That can cause patients to lose around 2% to 3% of their body weight within the ...