Search results
Results from the WOW.Com Content Network
Components that are essential for osteoblast bone formation include mesenchymal stem cells (osteoblast precursor) and blood vessels that supply oxygen and nutrients for bone formation. Bone is a highly vascular tissue, and active formation of blood vessel cells, also from mesenchymal stem cells, is essential to support the metabolic activity of ...
HAADF-STEM electron image of a maturing osteocyte (preosteocyte or osteoid osteocyte) at the bone surface, appearing directly above osteoblast-like precursor cells (decalcified matrix). Note the elongated cell processes that are surrounded by the collagen type I matrix and already crossing lamellar boundaries as collagen (and eventually mineral ...
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Donate; Pages for logged out editors learn more
The osteoblast then deposits calcium phosphate which is hardened by hydroxide and bicarbonate ions. The brand-new bone created by the osteoblast is called osteoid. [24] Once the osteoblast is finished working it is actually trapped inside the bone once it hardens. When the osteoblast becomes trapped, it becomes known as an osteocyte.
Bone is broken down by osteoclasts, and rebuilt by osteoblasts, both of which communicate through cytokine (TGF-β, IGF) signalling. Ossification (also called osteogenesis or bone mineralization) in bone remodeling is the process of laying down new bone material by cells named osteoblasts. It is synonymous with bone tissue formation. [1]
After the bone is completely ossified, the osteoblasts retract their calcium phosphate secreting tendrils, leaving tiny canals in the bony matrix, known as canaliculi. These canaliculi provide the nutrients needed for the newly transformed osteoblasts, which are now called osteocytes. These cells are responsible for the general maintenance of ...
Bone is resorbed by osteoclasts, and is deposited by osteoblasts in a process called ossification. [6] Osteocyte activity plays a key role in this process. Conditions that result in a decrease in bone mass can either be caused by an increase in resorption or by a decrease in ossification. During childhood, bone formation exceeds resorption.
Bone canaliculi are microscopic canals between the lacunae of ossified bone.The radiating processes of the osteocytes (called filopodia) project into these canals. These cytoplasmic processes are joined together by gap junctions.