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Neuroplasticity, also known as neural plasticity or just plasticity, is the ability of neural networks in the brain to change through growth and reorganization. Neuroplasticity refers to the brain's ability to reorganize and rewire its neural connections, enabling it to adapt and function in ways that differ from its prior state.
Neuroplasticity is the process by which neurons adapt to a disturbance over time, and most often occurs in response to repeated exposure to stimuli. [27] Aerobic exercise increases the production of neurotrophic factors [note 1] (e.g., BDNF, IGF-1, VEGF) which mediate improvements in cognitive functions and various forms of memory by promoting blood vessel formation in the brain, adult ...
In 1973, M. M. Taylor [1] suggested that if synapses were strengthened for which a presynaptic spike occurred just before a postsynaptic spike more often than the reverse (Hebbian learning), while with the opposite timing or in the absence of a closely timed presynaptic spike, synapses were weakened (anti-Hebbian learning), the result would be an informationally efficient recoding of input ...
Early LTP is best studied in the context of classical conditioning. As the signal of an unconditioned stimulus enters the pontine nuclei in the brainstem, the signal travels through the mossy fibres to the interpositus nucleus and the parallel fibres in the cerebellum.
Mark Richard Rosenzweig (September 12, 1922 – July 20, 2009) was an American research psychologist whose research on neuroplasticity in animals indicated that the adult brain remains capable of anatomical remodelling and reorganization based on life experiences, overturning the conventional wisdom that the brain reached full maturity in childhood.
Two molecular mechanisms for synaptic plasticity involve the NMDA and AMPA glutamate receptors. Opening of NMDA channels (which relates to the level of cellular depolarization) leads to a rise in post-synaptic Ca 2+ concentration and this has been linked to long-term potentiation, LTP (as well as to protein kinase activation); strong depolarization of the post-synaptic cell completely ...
The Wisconsin Card Sorting Test (WCST) is a neuropsychological test of set-shifting, which is the capability to show flexibility when exposed to changes in reinforcement. [1] [2] The WCST was written by David A. Grant and Esta A. Berg.
Plasticity in the brain affects the strength of neural connections and pathways. Nonsynaptic plasticity is a form of neuroplasticity that involves modification of ion channel function in the axon, dendrites, and cell body that results in specific changes in the integration of excitatory postsynaptic potentials and inhibitory postsynaptic potentials.