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An alternative to statins may help reduce deaths from heart disease among people with high levels of LDL, or “bad” cholesterol, new research finds.. When taken as a daily pill, bempedoic acid ...
Statins are a popular cholesterol-reducing medication, but come with a risk of muscle aches and other uncomfortable side effects. New research finds that bempedoic acid may be an effective ...
Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug.In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [1]
New research finds that millions of people on statins may not need to be taking the drugs. Researchers came to this conclusion after updating the method of assessing an individual’s 10-year risk ...
Pitavastatin (usually as a calcium salt) is a member of the blood cholesterol lowering medication class of statins. [1] Pitavastatin is an inhibitor of HMG-CoA reductase, the enzyme that catalyses the first step of cholesterol synthesis. It was patented in 1987 and approved for medical use in 2003. [2] It is available in Japan, South Korea and ...
Alirocumab, sold under the brand name Praluent, is a medication used as a second-line treatment for high cholesterol for adults whose cholesterol is not controlled by diet and statin treatment. It is a human monoclonal antibody that belongs to a novel class of anti-cholesterol drugs, known as PCSK9 inhibitors , and it was the first such agent ...
A new way of determining heart disease risk may result in millions fewer people getting prescriptions for statins, according to new research. Heart doctors warned, however, that more information ...
These values were 77 nM, 66 nM and 176 nM for these statins, respectively, while the value for cerivastatin was found to be 1.1 nM. Using Dixon plots, the inhibitory constant of cerivastatin was found to be 1.3 x 10-9 M, which is over 100 times lower than the inhibitory constant of lovastatin, known to be 150 x 10-9 M. To compare cerivastatin ...