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(The Center Square) – The federal government reported a sharp increase in overdose deaths due to carfentanil, a powerful opioid 100 times stronger than fentanyl that veterinarians use on bears ...
The effects of carfentanil, including overdose, can be reversed by the opioid antagonists naloxone and naltrexone, though higher doses than usual may be necessary compared to other opioids. [1] [2] [3]: 23 Carfentanil is a structural analogue of the synthetic opioid analgesic fentanyl. [4]
Fentanyl has made headlines for driving overdose deaths, but the Centers for Disease Control and Prevention is warning of the rise of an even deadlier drug. ... Carfentanil is 10,000 more times ...
There is no broad-level data that tracks carfentanil overdose deaths, but a 2020 study from researchers at the University of Pittsburgh linked carfentanil in drug seizures to overall overdose ...
In February 2022, 24 people in Argentina died after using cocaine laced with carfentanil. [7] Reversing a gray death overdose may require multiple doses of naloxone. By contrast, an overdose from morphine or from high-purity heroin would ordinarily need only one dose. [5]
An opioid overdose is toxicity due to excessive consumption of opioids, such as morphine, codeine, heroin, fentanyl, tramadol, and methadone. [3] [5] This preventable pathology can be fatal if it leads to respiratory depression, a lethal condition that can cause hypoxia from slow and shallow breathing. [3]
Samples tested from bags labeled "Super Mario" were found to include carfentanil, a potent drug up to 100 times stronger than fentanyl. ... according to the county's opioid overdose tracker.
The weakest compounds such as benzylfentanyl are around the same potency as codeine (i.e. approximately 1/10th the potency of morphine), while the strongest compounds such as carfentanil and ohmefentanil can be over 10,000x more potent than morphine, meaning there is a 100,000-fold variation in potency between the strongest and weakest fentanyl ...