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Guaifenesin. Guaifenesin protocol is an unapproved treatment for fibromyalgia suggested in the 1990s by R. Paul St. Amand, M.D.The protocol involves three parts: titrating the guaifenesin dosage, avoiding salicylates, and following a low-carbohydrate diet if the patient is hypoglycemic.
In general, the safety and effectiveness of alternative medicines have not been scientifically proven [1] and remain largely unknown. [2] Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation , or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life ...
During its development for fibromyalgia, milnacipran was evaluated utilizing a composite responder approach.To be considered as a responder for the composite ‘treatment of fibromyalgia’ endpoint, each patient had to show concurrent and clinically meaningful improvements in pain, physical function, and global impression of disease status.
A systematic review of EEG neurofeedback for the treatment of fibromyalgia found most treatments showed significant improvements of the main symptoms of the disease. [232] However, the protocols were so different, and the lack of controls or randomization impede drawing conclusive results.
A 2014 Cochrane review concluded that duloxetine is beneficial in the treatment of diabetic neuropathy and fibromyalgia but that more comparative studies with other medicines are needed. [22] The French medical journal Prescrire concluded that duloxetine is no better than other available agents and has a greater risk of side effects. [23]
Conventional treatments are subjected to testing for undesired side-effects, whereas alternative therapies, in general, are not subjected to such testing at all. Any treatment – whether conventional or alternative – that has a biological or psychological effect on a patient may also have potential to possess dangerous biological or ...
[medical citation needed] Side effects such as sedation and ataxia are also less pronounced with nonbenzodiazepine antispasmodics. [ medical citation needed ] In a study on the treatment of musculoskeletal pain treatment with cyclobenzaprine alone or in combination with ibuprofen , no significant differences in pain scores were noted among the ...
Augmentation: [a] Especially when used to treat restless legs syndrome, long-term Pramipexole treatment may exhibit drug augmentation, which is "an iatrogenic worsening of RLS symptoms following treatment with dopaminergic agents" [24] and may include an earlier onset of symptoms during the day or a generalized increase in symptoms.