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Acetyl-L-carnitine, ALCAR or ALC, is an acetylated form of L-carnitine.It is naturally produced by the human body, and it is available as a dietary supplement. Acetylcarnitine is broken down in the blood by plasma esterases to carnitine which is used by the body to transport fatty acids into the mitochondria for breakdown and ener
There are a variety of genital surgeries available to trans women and transfeminine non-binary people. Genital surgery can be an effective way for an individual to ease or eliminate feelings of disconnection or discomfort with their natal genitals; for others, including those who do not feel strongly about their natal genitals, it can create feelings of connection or congruence with their ...
Intersex medical interventions (IMI), sometimes known as intersex genital mutilations (IGM), [1] are surgical, hormonal and other medical interventions performed to modify atypical or ambiguous genitalia and other sex characteristics, primarily for the purposes of making a person's appearance more typical and to reduce the likelihood of future problems.
The surgical procedure is typically done in two stages, but it is possible to conduct the surgery in one stage. The first stage is the discontinuation of the waste functions by performing a colostomy and ileal conduit in the upper abdominal quadrants. The second stage is the amputation at the lumbar spine. [5] [6]
Ovarian drilling was first used in the treatment of PCOS in 1984 and has evolved as a safe and effective surgery. [11] After performing laparoscopic electrosurgical ovarian drilling in CC-resistant patients in 1984, Gjönnaess found that this technique increased ovulation rates to 45 percent and pregnancy rates to 42 percent. [ 18 ]
The primary biological functions of carnitine in humans include the following: [8] fatty acid transport across the mitochondrial membrane by forming long-chain acylcarnitine esters which are shuttled into the mitochondria, where they undergo β-oxidation to produce ATP, the cell's main energy currency; [8]
57279 Ensembl ENSG00000178537 ENSMUSG00000032602 UniProt O43772 Q9Z2Z6 RefSeq (mRNA) NM_000387 NM_020520 RefSeq (protein) NP_000378 NP_065266 Location (UCSC) Chr 3: 48.86 – 48.9 Mb Chr 9: 108.54 – 108.56 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 Identifiers Symbol SLC25A20 Alt. symbols CACT NCBI gene ...
Carnitine-acylcarnitine translocase deficiency is a rare, autosomal recessive metabolic disorder that prevents the body from converting long-chain fatty acids into energy, particularly during periods without food. [1]