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Inflammaging (also known as inflamm-aging or inflamm-ageing) is a chronic, sterile, low-grade inflammation that develops with advanced age, in the absence of overt infection, and may contribute to clinical manifestations of other age-related pathologies.
T cells' functional capacity is most influenced by aging effects. Age-related alterations are evident in all T-cell development stages, making them a significant factor in immunosenescence. [27] T-cell function decline begins with the progressive involution of the thymus, which is the organ essential for T-cell maturation.
[59] [60] [61] A substantial body of evidence implicates chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency. [ 59 ] [ 62 ] Many now regard HIV infection not only as an evolving virus-induced immunodeficiency, but also as chronic inflammatory disease. [ 63 ]
After age 30, the mass of the human body is decreased until 70 years and then shows damping oscillations. [24] People over 35 years of age are at increasing risk for losing strength in the ciliary muscle of the eyes, which leads to difficulty focusing on close objects, or presbyopia. [27] [28] Most people experience presbyopia by age 45–50. [29]
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Academic age; Active ageing; Activist ageing; Age bias (medicine) Age management medicine; Ageing of newspaper readership; Ageing studies; Agequake; Ageing of Europe; The Aging Symposium (Alberta) Anti-aging product; Anti-aging movement; Anti-aging supplements; ARC Centre of Excellence in Population Ageing Research
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