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Observational studies in humans — which cannot show a direct cause and effect — saw an association between aspartame and liver, breast and lymphoma cancers, as well as an impact on type 2 ...
Trivia aside, the main present-day debate is around whether aspartame causes cancer. In July 2023, the World Health Organization (WHO) put aspartame on a list of ingredients that are “ possibly ...
The IARC said in a release Thursday that it was classifying aspartame as possibly carcinogenic, meaning there is some evidence that it may cause cancer in humans, but that the evidence is far from ...
[6] [7] [8] [1] [9] In mice, high levels of Lac-Phe in the blood cause a decrease of food intake [6] and in humans, its production has been shown to correlate with adipose tissue loss during an endurance exercise intervention. [10] In mammals it is created from -lactate and L-phenylalanine by the cytosol nonspecific dipeptidase (CNDP2) protein. [1]
Tetrahydrobiopterin deficiency (THBD, BH 4 D) is a rare metabolic disorder that increases the blood levels of phenylalanine.Phenylalanine is an amino acid obtained normally through the diet, but can be harmful if excess levels build up, causing intellectual disability and other serious health problems.
A small subset of patients with hyperphenylalaninemia shows an appropriate reduction in plasma phenylalanine levels with dietary restriction of this amino acid; however, these patients still develop progressive neurologic symptoms and seizures and usually die within the first 2 years of life ("malignant" hyperphenylalaninemia).
The IARC panel said on Friday it had made its ruling based on three studies in humans in the United States and Europe that indicated a link between hepatocellular carcinoma, a form of liver cancer ...
Phenylalanine ball and stick model spinning. Phenylalanine (symbol Phe or F) [3] is an essential α-amino acid with the formula C 9 H 11 NO 2.It can be viewed as a benzyl group substituted for the methyl group of alanine, or a phenyl group in place of a terminal hydrogen of alanine.