Search results
Results from the WOW.Com Content Network
Reactive airway disease (RAD) is an informal label that physicians apply to patients with symptoms similar to those of asthma. [1] An exact definition of the condition does not exist. [ 1 ] [ 2 ] Individuals who are typically labeled as having RAD generally have a history of wheezing, coughing, dyspnea , and production of sputum that may or may ...
Bronchial hyperresponsiveness (or other combinations with airway or hyperreactivity, BH used as a general abbreviation) [1] is a state characterised by easily triggered bronchospasm (contraction of the bronchioles or small airways). Bronchial hyperresponsiveness can be assessed with a bronchial challenge test.
Exercise-induced bronchoconstriction (EIB) occurs when the airways narrow as a result of exercise. This condition has been referred to as exercise-induced asthma (EIA); however, this term is no longer preferred. [1] While exercise does not cause asthma, it is frequently an asthma trigger. [1]
Reactive airways dysfunction syndrome (RADS) is a severe form of irritant induced asthma where respiratory symptoms usually develop in the minutes or hours after a single accidental inhalation of a high concentration of irritant gas, aerosol, vapor, or smoke. [3]
Airway remodelling, or airway remodeling, is a potential complication of certain endotypes (subtypes) of asthma. It is the sum of changes that occur in the airways of some asthmatic people compared to people without the disease.
Inflamed airways are more hyper-reactive, and will be more prone to bronchospasm. The " hygiene hypothesis " postulates that in early life, an imbalance in the regulation of these T H cell types leads to a long-term domination of the cells involved in allergic responses over those involved in fighting infection.
The airways have a tone baseline, and consequently a baseline level of contraction of their smooth musculature. Airway tone is a key determinant of lung function and the presence of respiratory symptoms in obstructive lung diseases such as asthma, where baseline airway tone is elevated. [2]
Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.