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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    The results of the negotiations were announced in August 2024, and Medicare's negotiated price for a 30-day supply of Eliquis is $231, a 56% decrease from the 2023 list price of $521. [42] The pricing is set to take effect in 2026. [43] [44]

  3. Drug packaging - Wikipedia

    en.wikipedia.org/wiki/Drug_packaging

    The primary component of a blister pack is a cavity or pocket made from a thermoformed plastic. This usually has a backing of paperboard or a lidding seal of aluminum foil or plastic film . Blister packs are useful for protecting drugs against external factors, such as humidity and contamination for extended periods of time.

  4. Supply chain risk management - Wikipedia

    en.wikipedia.org/wiki/Supply_Chain_Risk_Management

    Supply-chain risk management is aimed at managing risks in complex and dynamic supply and demand networks. [1] (cf. Wieland/Wallenburg, 2011)Supply chain risk management (SCRM) is "the implementation of strategies to manage both everyday and exceptional risks along the supply chain based on continuous risk assessment with the objective of reducing vulnerability and ensuring continuity".

  5. Supply chain management - Wikipedia

    en.wikipedia.org/wiki/Supply_chain_management

    A supply chain is the network of all the individuals, organizations, resources, activities and technology involved in the creation and sale of a product. A supply chain encompasses everything from the delivery of source materials from the supplier to the manufacturer through to its eventual delivery to the end user.

  6. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]

  7. List of largest selling pharmaceutical products - Wikipedia

    en.wikipedia.org/wiki/List_of_largest_selling...

    Eliquis 9872 7395 4 lenalidomide: multiple myeloma: Revlimid 9685 8187 5 nivolumab: oncology: Opdivo 7570 5763 6 pembrolizumab: oncology: Keytruda 7171 3809 7 etanercept: rheumatoid arthritis: Enbrel 7126 7885 8 trastuzumab: breast cancer: Herceptin 6981 7013 9 bevacizumab: colon cancer: Avastin 6847 6686 10 rituximab: non-Hodgkin's lymphoma ...

  8. 2021–2023 global supply chain crisis - Wikipedia

    en.wikipedia.org/wiki/2021–2023_global_supply...

    It will have an impact on the global supply chain as Russia is a significant source of 35 critical minerals vital to the United States' economic and national security interests, including 30% of the global supply of platinum-group elements (including palladium), 13% of titanium and 11% of nickel.

  9. Bullwhip effect - Wikipedia

    en.wikipedia.org/wiki/Bullwhip_effect

    The first theories focusing onto the bullwhip effect were mainly focusing on the irrational behavior of the human in the supply chain, highlighting them as the main cause of the bullwhip effect. Since the 90's, the studies evolved, placing the supply chain's misfunctioning at the heart of their studies abandoning the human factors. [5]

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