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Sentinel cells refer to cells in the body's first line of defense, which embed themselves in tissues such as skin. [1] Sentinel cells represent diverse array of cell types with the capability to monitor the presence of exogenous or potentially harmful particles and play a crucial role in recognizing and sampling signs of infection or abnormal cellular activity and/or death.
Bridgeville, California (population 25) was the first town to be sold on eBay in 2002, and has been up for sale three times since. [1] In January 2003, Thatch Cay, the last privately held and undeveloped U.S. Virgin Island, was listed for auction by Idealight International. The minimum bid was US$3 million and the sale closed January 16, 2003. [2]
The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 98 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 99 ]
IC 50 values are typically expressed as molar concentration. IC 50 is commonly used as a measure of antagonist drug potency in pharmacological research. IC 50 is comparable to other measures of potency, such as EC 50 for excitatory drugs. EC 50 represents the dose or plasma concentration required for obtaining 50% of a maximum effect in vivo. [1]
The Sentinel A4 is a complete redesign of the sensor that uses digital processing and solid-state antenna modules based on gallium nitride (GAN) transmitters. The scalable modular architecture is shared with the long-range AN/TPY-4 radar, which has 1000 individually controlled elements and uses GPU computing for signal processing.
Triton X-100 is a commonly used detergent in laboratories. [5] Triton X-100 is widely used to lyse cells to extract protein or organelles, or to permeabilize the membranes of living cells. [6] Some applications include: Inactivation of lipid-enveloped viruses (e.g. HIV, HBV, HCV) in manufacturing of biopharmaceuticals; Industrial purpose ...
Fresh normal plasma has all the blood coagulation factors with normal levels. If the problem is a simple factor deficiency, mixing the patient plasma 1:1 with plasma that contains 100% of the normal factor level results in a level ≥50% in the mixture (say the patient has an activity of 0%; the average of 100% + 0% = 50%). [3]
An acute anticholinergic syndrome is reversible and subsides once all of the causative agents have been excreted. Reversible acetylcholinesterase inhibitor agents such as physostigmine can be used as an antidote in life-threatening cases. Wider use is discouraged due to the significant side effects related to cholinergic excess including ...
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