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Oxandrolone is an androgen and synthetic anabolic steroid (AAS) medication to help promote weight gain in various situations, to help offset protein catabolism caused by long-term corticosteroid therapy, to support recovery from severe burns, to treat bone pain associated with osteoporosis, to aid in the development of girls with Turner syndrome, and for other indications.
[3] [12] It has strong anabolic effects and weak androgenic effects, which give it a mild side effect profile and make it especially suitable for use in women and children. [3] [12] [13] NPP is a nandrolone ester and a long-lasting prodrug of nandrolone in the body. [3] NPP was first described in 1957 and was introduced for medical use in 1959. [3]
Oxandrolone (Anavar) (Note that while the above anabolic steroids remain available in at least one formulation, many of the above-listed brand names have been discontinued.) Ethylestrenol (Maxibolin) and stanozolol (Winstrol) were previously available but were discontinued.
Treatment of breast cancer in women, although they are now very rarely used for this purpose due to their marked virilizing side effects. [43] [18] [44] In low doses as a component of hormone therapy for postmenopausal and transgender women, for instance to increase energy, well-being, libido, and quality of life, as well as to reduce hot flashes.
In women, nandrolone and nandrolone esters have been reported to produce increased libido, acne, facial and body hair growth, voice changes, and clitoral enlargement. [20] However, the masculinizing effects of nandrolone and its esters are reported to be slighter than those of testosterone . [ 20 ]
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In women, side effects also include acne, changes in menstrual periods, voice deepening, hair growth on the chin or chest, pattern hair loss, enlarged clitoris, and changes in libido. [ 5 ] [ 15 ] Because of its 17α-alkylated structure, oxymetholone is hepatotoxic . [ 5 ]
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